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pipeline

We're growing a robust R&D program on several targets to prevent or treat bacterial infections.​
dermatology
BMBL7 - acne vulgaris
INCI: Palmitoyl Pentapeptide-75 Tripeptide-44 s-Oriental Fire-Bellied Toad Oligopeptide-1 Amide
Target: Cutibacterium acnes (C. acnes)
discovery
in-vitro testing
ex-vivo testing
safety
efficacy
commercialization
BMBL7 is a fusion antimicrobial peptide that consists of I) a quorum sensing motif which is a species-specific short peptide derived from the S-ribosylhomocysteine lyase gene of C. acnes that facilitates binding to the cell wall membrane, and II) a modified Bombinin-like peptide 7 moiety that rapidly abolishes the cell membrane integrity of the bacteria which instantly kills it.
BMBL10 - dermatitis
INCI: In progress
Target: Staphylococcus aureus (S. aureus)
discovery
in-vitro testing
ex-vivo testing
safety
efficacy
commercialization
BMBL7 is a fusion antimicrobial peptide that consists of I) a quorum sensing motif which is a species-specific short peptide derived from the S-ribosylhomocysteine lyase gene of S. areus that facilitates binding to the cell wall membrane, and II) a modified Bombinin-like peptide 7 moiety that rapidly abolishes the cell membrane integrity of the bacteria which instantly kills it.
pulmonary infections
BMBL14 - multi-drug resistant pulmonary tuberculosis
Target: Mycobacterium tuberculosis (M. tuberculosis)
poc
pre-clinical
phase 1
phase 2
phase 3
leader
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partner
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BMBL14 is a fusion endolysin that consists of I) a modified endolysin derived from mycobacteriophage TM4 , and II) a modified Bombinin-like peptide 7 moiety that facilitates increased binding efficacy, improved antibacterial properties, and improved thermostability.
BMBL15 - Multidrug-resistant Klebsiella pneumoniae
Target: Klebsiella pneumoniae (K. pneumoniae)
poc
pre-clinical
phase 1
phase 2
phase 3
leader
bombi-logo-wit.png
partner
logodendropharm.png
BMBL15 is a fusion endolysin that consists of I) a modified endolysin derived from Klebsiella phage SH-KP152226 , and II) a modified Bombinin-like peptide 7 moiety that facilitates increased binding efficacy, improved antibacterial properties, and improved thermostability.
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